Maintained drug concentration at the site of disease

ZILRETTA microspheres maintained quantifiable concentrations of triamcinolone acetonide (TA) in the synovial fluid out to 12 weeks1

Joint residence time chart
  • Results based on a study evaluating concentration of TA in synovial fluid following a single intra-articular injection of ZILRETTA® (triamcinolone acetonide extended-release injectable suspension) (n=29); synovial fluid was obtained at Weeks 1, 6, 12, 16, or 201

The clinical relevance of this synovial fluid information is unknown

*Data presented as geometric mean (GM). While GM is above the limit of quantification at Weeks 6 and 12, the range includes some patients who were below the limit of quantification (BLOQ).1

TA=triamcinolone acetonide; BLOQ=below the limit of quantification; GM=geometric mean.