Prolonged presence throughout 12 weeks
ZILRETTA microspheres maintained quantifiable concentations of triamcinolone acetonide (TA) in the synovial fluid through 12 weeks after a single injection1
Results based on a pharmacokinetic study evaluating concentration of TA in synovial fluid following a single IA injection of ZILRETTA (n=29) or TAcs (n=8). Synovial fluid was obtained at Weeks 1, 6, 12, 16, or 20 for ZILRETTA, or Week 6 for TAcs1
The clinical relevance of this synovial fluid information is unknown
*Data presented as geometric mean (GM). While GM is above the limit of quantification at Weeks 6 and 12, the range includes some patients who were below the limit of quantification (BLOQ).2
BLOQ=below the limit of quantification; GM=geometric mean; TA=triamcinolone acetonide.